Cinnamon Bark- some evidence

 Cinnamaldehyde, the main chemical constituent of Cinnamon Bark and Cassia essential oils has a warm, inviting aroma. A study printed in the June 2015 issue of the Journal of Cellular Biochemistry suggests that cinnamaldehyde acts to support healthy molecular function in the kidneys but further studies need to be carried out to fully understand the effects of this oil. This study showed that cinnamaldehyde inactivated the JAK2-STAT1/STAT3 biochemical pathway in the kidney cells, which may help keep kidney cells healthy. Furthermore, another recent study highlighted Cinnamaldehyde' s effect as an antibacterial agent This study combined antibiotic doxycycline with isolated components of 3 essential oils, one of which being cinnamon – with all three components (carvacol, eugenol, cinnamaldehyde) found in both cinnamon leaf and bark oils. The combination had a synergistic effect and this could give us some answers regarding the problem of antibiotic resistance.

Additionally Cinnamon used as a spice can have a positive effect on diabetes . Recent research is investigating the mechanism by which this works, and some studies have found that some compounds, found in the essential oil, have the beneficial effect
Cinnamaldehyde in an animal model has been reported to reduce glucose levels and normalise responses in circulating blood. In 2015, researchers found cinnamic acid to improve glucose tolerance and potentially stimulate insulin production.

Huang J-S, Lee Y-H, Chuang L-Y, Guh J-Y, Hwang J-Y. Cinnamaldehyde and nitric oxide attenuate advanced glycation end products-induced the Jak/STAT signaling in human renal tubular cells. J Cell Biochem. 2015;116(6):1028-1038.

Valcourta,C.,Saulniera,A.,Umerskaa,M,,Zanellib,P.,Montagua,A.,Rossinesc,E.,Joly-Guilloub,M.L.(2016). Interactions between doxycycline and terpenic components of essential oils encapsulated within lipid nanocapsules against gram negative bacteria. International Journal of Pharmaceutics 498, (1–2), 23-31.

Davis, PA., Yokoyama, W. (2011) Cinnamon intake lowers fasting blood glucose: meta-analysis. J Med Food 14(9):884-9.

Subash Babu,P, Prabuseenivasan,S., Ignacimuthu,S. (2006) Cinnamaldehyde—A potential antidiabetic agent. Phytomedicine 14, (1) 15-22.

Cinnamic acid exerts anti-diabetic activity by improving glucose tolerance in vivo and by stimulating insulin secretion in vitro.

Hafizur, R.M., Hameed, A., Shukrana, M., Raza S.A., Chishti, S,. Kabir N., Siddiqui R.A (2015) Cinnamic acid exerts anti-diabetic activity by improving glucose tolerance in vivo and by stimulating insulin secretion in vitro. Phytomedicine 15;22(2):297-300. doi: 10.1016/j.phymed.2015.01.003